Identification of PGC7, a new gene expressed specifically in preimplantation embryos and germ cells

نویسندگان

  • Masatake Sato
  • Tohru Kimura
  • Ken Kurokawa
  • Yukiko Fujita
  • Koichiro Abe
  • Masaaki Masuhara
  • Teruo Yasunaga
  • Akihide Ryo
  • Mikio Yamamoto
  • Toru Nakano
چکیده

The gene expression patterns of primordial germ cells (PGCs) and embryonic stem cells were analyzed by a modified serial analysis of gene expression. During the process, we cloned a novel gene, PGC7, which was preferentially expressed in PGCs. Immunohistochemical analysis revealed that PGC7 was specifically expressed in early pre-implantation embryos, PGCs and oocytes. These results suggest that PGC7 might play an important role in the development of PGCs and oocytes.

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عنوان ژورنال:
  • Mechanisms of Development

دوره 113  شماره 

صفحات  -

تاریخ انتشار 2002